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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYNGAP1
All Species:
6.36
Human Site:
Y100
Identified Species:
15.56
UniProt:
Q96PV0
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PV0
NP_006763.2
1343
148284
Y100
R
P
H
G
E
H
E
Y
H
L
G
R
S
R
R
Chimpanzee
Pan troglodytes
XP_514024
1280
143851
Y94
T
T
T
W
E
R
K
Y
C
I
L
T
D
S
Q
Rhesus Macaque
Macaca mulatta
XP_001109824
1284
140910
R93
K
S
Q
P
K
L
D
R
T
S
S
F
R
Q
I
Dog
Lupus familis
XP_538863
1173
131030
C38
P
G
W
N
P
R
F
C
I
I
S
G
N
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3UHC7
1189
131708
L54
R
P
G
S
R
R
S
L
P
G
S
M
S
E
K
Rat
Rattus norvegicus
Q9QUH6
1308
144704
Y100
R
P
H
G
E
H
E
Y
H
L
G
R
S
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512503
1229
137115
S93
A
Q
R
R
S
M
P
S
G
L
S
E
K
T
P
Chicken
Gallus gallus
XP_415400
1177
132324
P42
P
L
S
R
E
S
P
P
E
R
C
G
Q
R
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690883
1278
143168
Q93
K
S
F
A
T
S
R
Q
R
S
M
E
T
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T498
1580
173511
I139
K
S
K
T
L
P
R
I
H
F
D
T
A
L
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.7
94.1
85.9
N.A.
47.7
96.1
N.A.
46
48
N.A.
53.3
N.A.
27.7
N.A.
N.A.
N.A.
Protein Similarity:
100
63.7
94.3
86.1
N.A.
63.2
96.6
N.A.
62.4
64.1
N.A.
66.1
N.A.
44.4
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
0
0
N.A.
20
100
N.A.
6.6
20
N.A.
0
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
26.6
20
N.A.
26.6
100
N.A.
6.6
20
N.A.
13.3
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
10
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
10
0
10
0
0
% D
% Glu:
0
0
0
0
40
0
20
0
10
0
0
20
0
10
0
% E
% Phe:
0
0
10
0
0
0
10
0
0
10
0
10
0
0
0
% F
% Gly:
0
10
10
20
0
0
0
0
10
10
20
20
0
0
0
% G
% His:
0
0
20
0
0
20
0
0
30
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
10
20
0
0
0
0
10
% I
% Lys:
30
0
10
0
10
0
10
0
0
0
0
0
10
0
10
% K
% Leu:
0
10
0
0
10
10
0
10
0
30
10
0
0
10
10
% L
% Met:
0
0
0
0
0
10
0
0
0
0
10
10
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
10
% N
% Pro:
20
30
0
10
10
10
20
10
10
0
0
0
0
10
20
% P
% Gln:
0
10
10
0
0
0
0
10
0
0
0
0
10
20
10
% Q
% Arg:
30
0
10
20
10
30
20
10
10
10
0
20
10
30
30
% R
% Ser:
0
30
10
10
10
20
10
10
0
20
40
0
30
10
0
% S
% Thr:
10
10
10
10
10
0
0
0
10
0
0
20
10
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
30
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _